Publication: The Role of Parathyroid Hormone Level as a Predictor of Hypocalcemia After Total Thyroidectomy for Thyroid Cancer: A Cross-Sectional Study
| dc.contributor.author | Semanate, Fernando | |
| dc.contributor.author | Tarupi, Wilmer | |
| dc.contributor.author | Fernandez Trokhimtchouk, Tatiana | |
| dc.contributor.author | Palacios, Christian | |
| dc.contributor.author | Jaramillo, Oscar | |
| dc.date.accessioned | 2026-04-10T17:57:48Z | |
| dc.date.available | 2026-04-10T17:57:48Z | |
| dc.date.issued | 2025 | |
| dc.description.abstract | This study aimed to investigate the utility of measuring parathyroid hormone (PTH) levels as a predictor of hypocalcemia in a population of patients undergoing total thyroidectomy for thyroid cancer between 2016 and 2019. We conducted an observational, analytical, descriptive, cross-sectional investigation, assessing PTH levels as a predictor of hypocalcemia following thyroidectomy. Among patients with hypoparathyroidism, 25.5% experienced hypocalcemia, while 74.5% had normal serum calcium levels. The likelihood of hypocalcemia was five times higher in patients with hypoparathyroidism (OR: 5.43; 95% CI: 1.89-15.6), a statistically significant finding (p < 0.05). Additionally, PTH values at 24 hours post-surgery averaged 28.9 pg/mL (SD: 30.8 pg/mL), ranging from 0.01 to 235 pg/mL. Serum calcium levels averaged 8.31 mg/dL (SD: 0.74), with values ranging from 6.5 to 10.6 mg/dL. The study demonstrates a statistically significant association between PTH levels and post-surgical serum calcium levels, albeit with moderate predictive power. These findings support the utility of PTH measurement in predicting hypocalcemia following thyroidectomy, underscoring its potential clinical relevance in patient management. Keywords: low calcium; open thyroidectomy; parathyroid level; postoperative parathyroid hormone (pth); thyroid cancer surgery; thyroidectomy complications. | |
| dc.identifier.citation | Semanate, F., Tarupi, W., Fernandez Trokhimtchouk, T., Palacios, C., & Jaramillo, O. (2025). The Role of Parathyroid Hormone Level as a Predictor of Hypocalcemia After Total Thyroidectomy for Thyroid Cancer: A Cross-Sectional Study. Cureus, 17(2), e78897. https://doi.org/10.7759/cureus.78897 | |
| dc.identifier.uri | https://biblioteca.solcaquito.org.ec/handle/123456789/1752 | |
| dc.language.iso | en | |
| dc.title | The Role of Parathyroid Hormone Level as a Predictor of Hypocalcemia After Total Thyroidectomy for Thyroid Cancer: A Cross-Sectional Study | |
| dc.type | Article | |
| dspace.entity.type | Publication |