Acute Respiratory Failure Due to Paraneoplastic Syndrome Associated with Eosinophilic Pneumonia in a Patient with Seminoma: A Case Report

Abstract
Background: Acute eosinophilic pneumonia as a paraneoplastic syndrome is an infrequent finding, produces Acute Respiratory Dis-tress Syndrome (ARDS) with a fatal outcome, and is associated with a poor oncological prognosis. Case Summary: 27-year-old male patient with a history of weight loss three months before admission, asthenia, and night sweats; a month before lymphadenopathy in cervical, inguinal, and axillary lymph node chains, associated with a dry cough that progresses to moderate hemoptysis, with worsening of the symptoms, a requirement for home oxygen (3L), persistence of hemoptysis, and constitutional symptoms, went to the hospital. The patient was admitted to the ICU with ARDS. After ruling out other pathologies, based on the clinical and tomographic findings, it is considered eosinophilic pneumonia. Under treatment with corticosteroid therapy, the patient experiences an improvement in his clinical condition. Conclusion: Acute respiratory failure associated with eosinophilic pneumonia and peripheral eosinophilia constitutes a complexclinical condition that requires diagnostic expertise to guarantee timely treatment. Although they respond favorably to treatment, the presence of these elements in the context of cancer is associated with an unfavorable prognosis. Keywords: Acute eosinophilic pneumonia; Paraneoplastic syndrome; Paraneoplastic disorder; Respiratory failure; Pulmonary eosinophilia; Seminoma Core Tip Acute Respiratory Distress Syndrome (ARDS) caused by para- neoplastic eosinophilic pneumonia in the context of secondary immune response to cancer, especially in the case of seminoma, is an infrequent phenomenon. It manifests itself in both solid and hematological tumors, and its presence is linked to a dismal oncological prognosis. Diagnosing this condition presents significant challenges, requiring rapid and accurate identification to guarantee the prompt implementation of timely treatment. We present the first case of metastatic seminoma in a 23-year-old man admitted to the Intensive Care Unit (ICU) for respiratory failure-type severe ARDS due to eosinophilic pneumonia as the main symptom
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Citation
García Aguilera, MF. Basantes Borja, EE. Alexander-Leon, HA. Unigarro Quiñonez, LJ. Bonilla Poma, WC. Correa Álvarez, FR. Ortiz Navas, DA. García Méndez, N. (2024). Acute Respiratory Failure Due to Paraneoplastic Syndrome Associated with Eosinophilic Pneumonia in a Patient with Seminoma: A Case Report. J Fam Med. 2024; 11(4): 1363.